Ethical and Social Implications of Gene Editing

In the recent decade, many ethical, legal, and social concerns (ELSI) about genetic testing and research have been raised. These concerns should be raised with patients so that they are aware of the risks and benefits of genetic testing and may use it safely and correctly. This chapter provides a quick summary of some of the most critical ELSI questions surrounding genetic testing. Concerns have been raised about the use and possible commercialization of genome sequencing. Concerns range from a genetic test's analytical and clinical validity to the perceived stigma of having a genetic difference to the obligation to disclose genetic information to potentially impacted individuals.

  • Communicating test results
  • Direct-to-consumer tests
  • Duty to disclose
  • Genetic discrimination
  • Psychosocial impact
  • Reproductive issues

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