Track Categories
The track category is the heading under which your abstract will be reviewed and later published in the conference printed matters if accepted. During the submission process, you will be asked to select one track category for your abstract.
The scientific field concerned with the statistical method for the purpose of drawing inferences from genetic data. The statistical genetics is the developing field commonly used in the context of human genetics. The recent development in statistical genetics is the exploration of gene modules in single cell RNA- seq data by a tool MTGO-SC, which is the key step in the identification of the functional modules in gene interaction network for understanding biological process.
Human genetics deals with the examination of the inheritance that occurs in the human beings. The recent research in human genetics is on untangling the roots of lung cancer. The genomic and host factor that drive the progression of pre-invasive lesions in non-small cell lung cancer. On results of whole-exome sequencing of pre invasive lesions and LUADs the mutation burden increases as lesions in the airway progress from AAH to invasive disease.
Molecular Genetics deals with the evaluation of the structure and function of genes at a molecular level, it engages with the mechanism of both molecular biology and genetics. The recent development is based on the DNA, as a biological lens. It’s a new research in cell describes the technique of DNA microscopy, where the images of the spatial distribution of cell biomolecules are generated without direct visualization, by using DNA sequencing.
Medical genetics is the field of medicine that imply on the conclusion and the administration of the hereditary disorders. Genetic medicine consolidates in the sphere such as gene therapy, personalized medicine and in predictive medicine. The recent researches that are carried are based on the evolution that made the humans ‘fat’. In this research scientist have compared fat samples from human and other primates and found that changes in DNA packaging, scientist found changes to how DNA is packed inside fat cells to reduce the human body’s ability to turn bad fat into good fat.
Population genetics is the subset of genetics that bestow with the genetic variations within and allying inhabitants and it is fragment of evolutionary biology. The latest research is finding the Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs. The research states that that the large number of population has been studies and is applied to new population samples. The existing reference database of population samples allows the relationship of new samples to be inferred on a global level.
Clinical genetics deals with the proper dealing of rare disorders. The clinical genetic necessitate some customary formula. They are like: clinical history taking, physical examination, genetic testing, genetic counselling, performing skin biopsies, taking clinical snapshots, using computerised databases. The trending news is the discovery and validation of methylated-differentially expressed genes in helicobacter pylori that are induced o gastric cancer and new genetic cause for the infertility in male. Several diagnostic tests have been performed in few male and their parents for the comparison of the parental DNA with that of the offspring for the identification of the novo mutation.
Gene mapping is the method to identify the location of the gene and the distance between the genes. The genetic map can be built by the development of the genetic markers and a mapping population. The recent researches are based on the Reconstructing recent population history while mapping rare variants using haplotypes. The haplotype- based method is to characterize the in observed rare variants and map disease that is associated with alleles. Recently by using inflammatory bowel disease mapping two rare IBD haplotypes enriched with asthma patients has been identified.
Genomics the associative sphere of biology which spotlights on the structure, function, evolution, mapping and editing of genomes. Genomic has been emerged with new innovations like sequencing of human genomes with Nano pore technology. Nano pore technology has been extensively used for sequencing bacterial and viral genomes. Nano pore human genome sequencing achieves highly in identifying structural variations in patient sample
Mutation is the modification of the nucleotide sequence 0f the genome of an organism, virus or extra chromosomal DNA. A new immunodeficiency disease caused by a novel genetic mutation has been identified by researchers. The researchers investigated that the infants were suffering from inflammatory bowel disease. The mutation meant in this disease is that the natural killer cells were incapable of maturing properly and decrease in immune cells
Genetic analysis of DNA structure
A new DNA structure inside the human cell known as “i-motif” has been found by the scientists, it resembles like a knot of DNA. As we are well known with the double helix, but it was the first time it has been observed in living cells. The function of the i-motif is not sure, but is suspected to be involved in the process of reading DNA sequences and converting them into useful substances. To find the location of i-motifs inside human cells, the scientists designed tiny probes that could recognise the DNA knots. The scientist is still under their research to understand the benefit of the new DNA shape and its function on health and disease.
Gene therapy is the curative conveyance of nucleic acid into patient’s cells s drug to nurse disorders. Bone marrow transplantation and organ transplantation in general have been inaugurated to launch foreign
Genetic disorder is a complication spawned by the one or more malformation in the genome. The rising genetic disorders are the non- chromosomal birth defect that lead children to cancer like hepatoblastoma (liver cancer), neuroblastoma (cancer in adrenal gland) and chromosomal birth defect will include Down syndrome. The factors responsible for the birth defect is still a mystery, the researchers are identifying the children at increased risk of cancer because one day from screening and clinical management of that particular child will provide an uncover clue for the occurrence of the cancer.
Genetic counsellor is the person to help the couples, families, and an individual to understand their inherited genetic condition to make health decisions. Since they are trained in medical genetics a recent threat for genetic defect causing intellectual disability is been found. X –linked syndrome intellectual disability occurs by the genetic mutation that is being carried and passed by the unaffected females to their offspring but interesting note is that the symptoms are observed in male like behavioural issues, small average brains and testes.
The recent reviews are focused only on cancer in that way renal carcinoma occurs due to chromosomal aberration, in which the translocation of chromosomes occurs frequently, where the part of one chromosome can be found joined to another. The chromosomal abnormality can be of two types which includes Numerical abnormalities and structural abnormalities. The numerical abnormality is because of the alteration in one of the chromosomes or more than one chromosome. The structural abnormality is the alteration in the structure of the chromosomes.
As known cytogenetic deals with chromosomal structure, location of gene on chromosomes and chromosomal behaviour in cell division. The cytogenetic reviews in on-going chromosomal instability and karyotype evolution in human colorectal cancer organoids and evaluation of DNA interaction, genotoxicity and oxidative stress induced by iron oxide nanoparticles both in investor and in vivo, since iron particles are known to induce cytotoxicity in various cancer cell lines through generation of reactive oxygen species.
Diagnosis & Prognosis of Inborn Disorders
The genetic diagnosis remains unattainable for many individuals with rare disease because of the incomplete knowledge of the gene, the gene testing is a diagnosis method involves in detection of alleles, mutation, genotypes to karyotypes that are associated with heritable traits. The latest innovation in gene testing is about the characterization of the X-linked developmental disorder called Craniofrontonasal syndrome, occurs due to EFNB1 mutations and it illustrate the absence of correlation between the mutation type, severity and expression of symptoms.
Remedy for Hereditary Ailments
Since there is no known factors for curing genetic disorders, researches are under their process to find a solution for curing genetic disorders, in that way there comes a new study involving integrative genomic and transcriptomic analysis of dual hepatocellular-intrahepatic cholangiocarcinoma tumours has been identified that display different clinical and molecular features that would be used to guide therapeutic decisions. The remedy for genetic disorders is the on-going struggle with over large number of clinical trials has been completed. Despite of it some of the therapeutic options encircle in nursing the symptoms of the disorders to enhance the quality of life.
Genetic Epidemiology is characterized by an amalgam of strategies earned from customary the study of disease transmission, populace and family-based the study of disease transmission, from measurements, and critically, from bioinformatics. Together, explicit parts of these controls are applied to the investigation of qualities and condition, and of quality condition cooperations. Both quantitative and subjective qualities might be of intrigue. Hereditary the study of disease transmission utilizes novel case-control, family, and populace based plans, and genotyping from different sources.